Senior IT Engineer

Position Overview The Senior IT Engineer is a hands-on IT operational role on a small team supporting a fast-growing company. This role reports to the Director of IT and works closely with the IT Manager, Operations, Finance, and People Ops. This role is based onsite 5 days/week at our San Diego office.

You will own day-to-day operations of our core business infrastructure: identity, Microsoft 365, endpoint compliance, and the network alongside the IT Manager. You will also run the IT controls that support SOC 2 and future finance and SOX requirements.

Key Responsibilities Core business infrastructure

Administer and improve Okta, Microsoft 365 (Exchange Online, Entra ID, SharePoint), and Intune endpoint management for Windows and macOS. Own the identity lifecycle: role-based access at onboarding, the standard machine build, and clean, timely offboarding, in coordination with People Ops. Support the network (Meraki, FortiGate) with the IT Manager as lead: diagnose connectivity, Wi-Fi, and VPN issues, make routine changes, and escalate to our network partner when needed. Maintain endpoint security tooling and device compliance in coordination with the security program. Serve as a reliable backup across all core systems, so the business keeps running when other team members are out.

IT controls and compliance

Operate SOC 2 controls as routine process: access reviews, change records, evidence collection, and remediation. Build and operate IT controls for finance applications as they migrate in house, including access provisioning and review, separation of duties, change control, and audit logging. Build our business continuity and disaster recovery program, including backup design and tested recovery.

Operations and documentation

Handle escalated and complex service desk requests. Address recurring requests through root cause analysis and implementation of automated processes at onboarding, or through knowledge base articles and self-service solutions. Administer company AI tools such as Claude and ChatGPT, including access, licensing, usage guardrails, and use AI to automate IT work. Write and maintain clear documentation, runbooks, and procedures that meet audit approval standards. Lead IT projects end to end with minimal supervision.

Qualifications Education: Bachelor's degree in Information Technology, Computer Science, or a related field, or an equivalent combination of education, training, and direct experience.

Required

6+ years in corporate IT operations or systems administration, with independent ownership of production systems. Deep hands-on experience with Microsoft 365 and Entra ID, an identity provider such as Okta, and an MDM such as Intune. Hands-on network knowledge (switching, VLANs, Wi-Fi, firewalls, VPN) and the ability to troubleshoot methodically. Experience supporting audits or operating IT controls such as access reviews, change management, or evidence collection. Strong written documentation habits and clear communication with non-technical users.

Preferred

SOC 2, SOX ITGC, or NIST CSF experience. Experience with finance system controls (for example NetSuite), including separation of duties. Backup and disaster recovery design and testing. Scripting for automation (PowerShell, Python). Experience with CrowdStrike, zero-trust network access, and Jira Service Management. Experience in a biotech, life sciences, or other regulated, fast-growing companies -- prior start up experience desired.

What Success Looks Like

Core systems are reliable and documented well enough that the company runs smoothly even when the rest of the IT team is out. New hires get least privileged access and a working laptop on day one, and departures are fully offboarded the same day. SOC 2 controls operate continuously, with evidence produced as part of normal work rather than gathered after the fact. Finance application controls and a tested disaster recovery plan are in place ahead of audit and growth needs. Recurring requests decline over time because their root causes get fixed.

Why Join Us

A modern tech stack, no legacy cleanup. Okta, Microsoft 365, Intune, CrowdStrike, and zero-trust network access are already in place. AI is part of how we work. The IT team uses AI tools daily, and you'll help shape how the whole company adopts them safely. Greenfield work you'll own. Disaster recovery, finance controls, role-based access, and the standard build. Career-building compliance experience. Hands-on SOC 2 Type 2 and early SOX readiness. Real scope. A small IT team at a company that is growing fast, with direct access to IT leadership. Room to grow. Exposure to cloud infrastructure, life sciences data, and a new headquarters buildout. A mission worth joining. An experienced leadership team building something new in life sciences tools and diagnostics.

We offer competitive compensation and equity package, comprehensive benefits, and flexibility to support work-life priorities.

Radian Bio is an equal opportunity employer. We thrive on diversity and collaboration.